Endocrine Abstracts

67 y/o old female, with long history of hyperthyroidism, without treatment and hypertension. Two months prior to admission, she received amiodarone 200 mg daily due to cardiac arrhythmia. One week prior to admission, she developed symptoms of Congestive Heart Failure and weight loss. Family history: hyperthyroidism in two sisters. Physical examination: acutely ill, thin female, in moderate respiratory distress. Alert, oriented x 3.BP: 155/119 mmHg HR: 150.Prominent findings: m...

51 y/o female with past medical history of migraine headache, brought to UR because of hypoactivity, generalized weakness, confusion, lack of balance and dysarthria since one day of evolution. No medications. No Habits. Past history: negative for hypertension, cardiac disease or dyslipidemia. Physical examination: normal vital signs and weight. Alert, awake, and oriented only in person. Palpable nontender left thyroid lobe. Bilateral hyperreflexia.Labs: ...

A 30-year-old female presented to her general practitioner with a three-month history of fatigue, visual disturbance, polydipsia and dizziness. She was treated for iron deficiency anaemia, but re-presented two-months later with new-onset headache and worsening visual disturbance. Previously, she had childhood leukaemia, treated in Brazil with no cranial irradiation. On examination there was left eye loss of light/dark perception and right temporal vision loss. She was referred...

Background: There are no data concerning a relationship between alcohol and bone status of elderly Spanish men. Previous studies in other countries on the influence of alcohol intake on bone mineral density (BMD) in men are inconsistent and the effect of these variables on BMD is yet to be explored.Objective: The aim of this study was to describe the associations between total and beverage-specific alcohol intake and both BMD and bone ultrasound in elder...

Background: Human fibroblast growth factor 21 (FGF21) is a new liver hormone that stimulate adipocyte glucose uptake and is involved in regulation of body fat.Objective: To define the natural history of FGF21 in peritoneal dialysis (PD) patients and analyze its relationship with glucose metabolism, peritoneal function, and residual renal function (RRF).Methods: We studied 48 uremic patients undergoing PD. Patients were evaluated at...

Tight junctions (TJ) exist as macromolecular complexes comprised of several types of membrane proteins, cytoskeletal proteins and signaling molecules. Recently, it has been observed that some components are regulated during epithelial–mesenchymal transition in cancer cells; however, the effects of estradiol (E2) have been poorly studied. This study sought to determine the role of E2 on the expression and cell localization of the TJ-associated protein...